Drug Name:Dabigatran etexilate
Drug Class:Direct oral anticoagulant (DOAC)
Mechanism of Action:Inhibits thrombin, preventing the formation of blood clots
Use:
  • Prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation
  • Treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE)
  • Prevention of recurrent DVT and PE
Side Effects:
  • Bleeding (including gastrointestinal and intracranial bleeding)
  • Dyspepsia (indigestion)
  • Gastritis
  • Nausea
  • Abdominal pain
  • Headache
Contraindications:
  • Active bleeding
  • Mechanical prosthetic heart valve
  • Severe renal impairment (CrCl < 30 mL/min)
Specialty:
  • Cardiology
  • Hematology
  • Internal Medicine